Quinolines and derivatives

Medchemexpress LLC Chelerythrine chloride | 3895-92-9 | >98.0% | 5MG

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Chelerythrine chloride | 3895-92-9 | >98.0% | 5MG

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Medchemexpress LLC 1-cyclobutyl-3-(2,6-dimethylphenyl)-7-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-3,4-dihydropy | 2172617-15-9 | 99.8% | 50MG

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1-cyclobutyl-3-(2,6-dimethylphenyl)-7-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-3,4-dihydropy | 2172617-15-9 | 99.8% | 50MG

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Medchemexpress LLC Chelerythrine chloride | 3895-92-9 | >98.0% | 50 MG

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Chelerythrine chloride is a cell-permeable inhibitor of protein kinase C used in biochemical and cell biology research to study PKC-dependent signaling, apoptosis, and autophagy. It is supplied as a research-grade chemical with high purity.

• Cell-permeable protein kinase C inhibitor.
• Reported PKC IC50 660 nM.
• Inhibits Bcl-XL-Bak BH3 peptide binding (IC50 1.5 μM).
• Purity >98% by HPLC.
• Molecular formula C21H18ClNO4; molecular weight ~383.8 g/mol.
• Supplied as a 50 mg vial for research use.

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Medchemexpress LLC N-(1-benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide | 365565-02-2 | 99.3% | 25 MG

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PGP-4008 is a selective P-glycoprotein (Pgp) inhibitor used in research to study multidrug resistance and Pgp-mediated drug transport in cellular and animal models.

• Selective Pgp inhibitor for multidrug resistance research.
• Reported purity approximately 99.3% by primary supplier.
• CAS number 365565-02-2; molecular formula C26H23N3O; molecular weight 393.5 g/mol.
• Typically supplied as a 25 MG solid; soluble in DMSO.
• For research use only; follow appropriate handling and storage.

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Medchemexpress LLC N-(1-benzyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide | 365565-02-2 | 99.3% | 100 MG

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PGP-4008 is a selective P-glycoprotein (Pgp) inhibitor intended for research use. It has been shown to inhibit tumor growth in murine models of Pgp-mediated multidrug resistance when co-administered with doxorubicin.

• Selective P-glycoprotein inhibitor
• CAS 365565-02-2
• Purity 99.26%
• Molecular formula C26H23N3O
• Molecular weight 393.48 g/mol
• Available quantity 100 MG
• Provided as a powder; soluble in DMSO

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Medchemexpress LLC Pgp-4008 | 365565-02-2 | 99.3% | 1 ML

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PGP-4008 is a small-molecule P-glycoprotein inhibitor provided as a 10 mM solution in DMSO (1 mL) for in-vitro research. It is used to study Pgp-mediated multidrug resistance and transport assays, with high purity and characterized physicochemical data.

• Provided as 10 mM solution in DMSO, 1 mL
• High purity: 99.26%
• Molecular formula: C26H23N3O
• Molecular weight: 393.48 g/mol
• Solubility: DMSO soluble; ultrasonic and warming to 60°C recommended
• Storage: in solvent -80°C (6 months); -20°C (1 month)

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Medchemexpress LLC LM11A-31 5mg | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 5 MG

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LM11A-31 is a small-molecule ligand and modulator of the p75 neurotrophin receptor (p75NTR) used in preclinical research of neurodegenerative diseases. It is orally active, brain-penetrant, and provided for in vitro and in vivo studies in solid and solution formats.

• Small-molecule p75NTR modulator for neurodegeneration research.
• Orally active and brain-penetrant in preclinical studies.
• Available as a solid and as 10 mM solutions in DMSO for convenience.
• Identified by CAS 102562-74-3 and molecular formula C12H25N3O2.
• High reported purity (~99.9%) suitable for research applications.
• Commonly supplied in small research pack sizes such as 5 mg.

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Medchemexpress LLC Defactinib | 1073154-85-4 | 99.7% | 200 MG

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Defactinib is an orally bioavailable small-molecule focal adhesion kinase (FAK) inhibitor used in research to study antiangiogenic and antineoplastic mechanisms. Supplied as a white to off-white solid with high reported purity, it is commonly offered in multiple research pack sizes and solution formats for cellular assays.

• Orally bioavailable FAK inhibitor
• Inhibits FAK phosphorylation and downstream signaling pathways
• High reported purity (~99.7%) and supplied as a solid
• Available in multiple research pack sizes and DMSO solutions
• CAS number 1073154-85-4 and MFCD25977806 for identification

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eMolecules​ 59107-51-6 | 8-chloronaphthalen-1-amine | Synthonix | MFCD00465087 | 177.630 | C10H8ClN | 97.000 | Nc1cccc2cccc(Cl)c12 | 10g | 808551853

8-chloronaphthalen-1-amine | Synthonix | 59107-51-6 | MFCD00465087 | 177.630 | C10H8ClN | 97.000 | Nc1cccc2cccc(Cl)c12 | 10g | 808551853

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eMolecules​ 4965-36-0 | 7-bromoquinoline | Pharmablock | MFCD03695823 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2cccnc2c1 | 1g | 601586860

7-bromoquinoline | Pharmablock | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2cccnc2c1 | 1g | 601586860

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eMolecules​ 4965-36-0 | 7-bromoquinoline | Pharmablock | MFCD03695823 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2cccnc2c1 | 2.5g | 686944591

7-bromoquinoline | Pharmablock | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 97.000 | Brc1ccc2cccnc2c1 | 2.5g | 686944591

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eMolecules​ 59107-51-6 | 8-chloronaphthalen-1-amine | Pharmablock | MFCD00465087 | 177.630 | C10H8ClN | 97.000 | Nc1cccc2cccc(Cl)c12 | 25g | 551150670

8-chloronaphthalen-1-amine | Pharmablock | 59107-51-6 | MFCD00465087 | 177.630 | C10H8ClN | 97.000 | Nc1cccc2cccc(Cl)c12 | 25g | 551150670

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eMolecules​ 957486-82-7 | AZIDO-PEG6-AMINE | AstaTech | MFCD03453240 | 350.416 | C14H30N4O6 | 95.000 | NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 1g | 490832281

AZIDO-PEG6-AMINE | AstaTech | 957486-82-7 | MFCD03453240 | 350.416 | C14H30N4O6 | 95.000 | NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] | 1g | 490832281

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eMolecules​ 90905-32-1 | 2-Methoxypyrimidine-5-carbaldehyde | Synthonix - Stock | MFCD03446732 | 138.126 | C6H6N2O2 | 97.000 | COc1ncc(C=O)cn1 | 1g | 483373817

2-Methoxypyrimidine-5-carbaldehyde | Synthonix - Stock | 90905-32-1 | MFCD03446732 | 138.126 | C6H6N2O2 | 97.000 | COc1ncc(C=O)cn1 | 1g | 483373817

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Medchemexpress LLC RU.521 500mg | 2262452-06-0 | 500 MG

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RU.521 is a potent, selective small-molecule inhibitor of cyclic GMP-AMP synthase (cGAS) provided as a solid research chemical for in vitro and in vivo pathway and interferon-response studies.

• Potent and selective cGAS inhibitor.
• High purity suitable for research use.
• Chemical formula C19H12Cl2N4O3; molecular weight 415.23.
• Soluble in DMSO; in vivo formulation examples are reported.
• Available in multiple package sizes, including a 500 mg pack.
• Store powder at -20°C for long-term stability; in solvent storage recommendations provided.

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