Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1,981 – 1,995 of 4,396 results

1,981

Gold Biotechnology Inc Leupeptin Hemisulfate 5 mg

Leupeptin hemisulfate (Ac-Leu-Leu-argininal) is a reversible inhibitor of serine and cysteine endopeptidases Leupeptin hemisulfate is capable of inhibiting plasmin trypsin papain kallikrein calpain and cathepsin B Leupeptin is usually used in a concentration range of 10 to 100 M Leupeptin is widely used in many protease inhibitor cocktails due to its potency low toxicity and range of inhibition Leupeptin is also used in a quantitative assay to measure macroautophagic flux in mammals and is being investigated for its use in treating malaria

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1,982

MOLPORT INC 2 5-DIMETHOXY-N- QUINOLIN- 2UM

NC3232342 2 5-DIMETHOXY-N- QUINOLIN- 2UM

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1,983

Medchemexpress LLC MEDCHEMEXPRESS LLC

5000771962 MAL-C6-AMINE TFA 100MG

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1,984

eMolecules 39061-97-7 | 4-Chloro-3-nitroquinoline | Synthonix | MFCD07369246 | 208.600 | C9H5ClN2O2 | 95.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 25g | 831794068

4-Chloro-3-nitroquinoline | Synthonix | 39061-97-7 | MFCD07369246 | 208.600 | C9H5ClN2O2 | 95.000 | [O-][N+](=O)c1cnc2ccccc2c1Cl | 25g | 831794068

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1,985

Medchemexpress LLC Branaplam | 1562338-42-4 | 98.90% | 393.48 | 200 MG

Branaplam is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. It inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model.

Highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator.
Elevates full-length SMN protein.
Extends survival in a severe spinal muscular atrophy (SMA) mouse model.
EC50 of 20 nM for SMN.
IC50 of 6.3 μM for hERG.

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1,986

Sigma Aldrich Fine Chemicals Biosciences Ciprofloxacin hydrochloride European Pharmacopoeia (EP) Reference Standard | 86393-32-0 | MFCD00242856 |

Ciprofloxacin hydrochloride European Pharmacopoeia (EP) Reference Standard | Mol Wt: 385.82 | 86393-32-0 | MFCD00242856 |

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1,987

Medchemexpress LLC Dihydroergotamine mesylate | 6190-39-2 | 99.9% | 100 MG

Dihydroergotamine mesylate | 6190-39-2 | 99.9% | 100 MG

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1,988

Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | ≥98.0% | 1 G

Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker that can be used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker; one ligand is for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

PEG-based PROTAC linker
Used in the synthesis of PROTACs
Utilizes the intracellular ubiquitin-proteasome system
Selectively degrades target proteins

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1,989

eMolecules 36404-88-3 | 2-CHLORO-PYRIDINE-3-CARBALDEHYDE | AstaTech | MFCD01315308 | 141.550 | C6H4ClNO | 97.000 | Clc1ncccc1C=O | 100g | 206680064

2-CHLORO-PYRIDINE-3-CARBALDEHYDE | AstaTech | 36404-88-3 | MFCD01315308 | 141.550 | C6H4ClNO | 97.000 | Clc1ncccc1C=O | 100g | 206680064

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1,990

Medchemexpress LLC Nα-Boc-Nω-nitro-D-arginine | 50913-12-7 | MFCD00038091 | 25g

Afatinib impurity 7 (Boc-D-Arg(NO2)-OH) is an impurity of Afatinib (HY-10261)

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1,991

Selleck Chemical LLC Resiquimod

Resiquimod (R-848 S28463) is an immune response modifier that acts as a potent TLR 7/TLR 8 agonist that induces the upregulation of cytokines such as TNF- IL-6 and IFN- Resiquimod reduces hepatitis C virus (HCV) infection Phase 2

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1,992

Sigma Aldrich Fine Chemicals Biosciences 2-Hydroxyquinoline 98% | 59-31-4 | MFCD00006743 | 1G

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1,993

Medchemexpress LLC Trimethobenzamide hydrochloride | 554-92-7 | 99.9% | 200 MG

Trimethobenzamide hydrochloride is a non-phenothiazine benzamide antiemetic that acts centrally to block D2 receptors. It inhibits the medullary chemoreceptor trigger zone, blocking emetic impulses to prevent nausea and vomiting.

Acts as a blocker of the D2 receptor
Used to prevent nausea and vomiting
Exhibits 60% to 100% oral bioavailability
Achieves peak effect approximately 45 minutes after oral administration
Achieves peak effect approximately 30 minutes after intramuscular administration

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1,994

Medchemexpress LLC Pazufloxacin (mesylate) | 163680-77-1 | 100.0% | 1 ML

Pazufloxacin mesylate is an orally active fluoroquinolone antimicrobial agent. It inhibits DNA gyrase with IC50 values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). This agent exhibits broad-spectrum antimicrobial activity with MIC90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. It is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia.

Orally active fluoroquinolone antimicrobial agent
Inhibits DNA gyrase
Exhibits broad-spectrum antimicrobial activity against a variety of bacteria, including gram-positive, gram-negative, non-fermenting, Legionella spp., and anaerobic bacteria
Indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia

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1,995

TARGETMOL CHEMICALS INC ON-01910 25MG

Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells.It is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity. purity: 99%

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Quinolines and derivatives

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Gold Biotechnology Inc Leupeptin Hemisulfate 5 mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MEDCHEMEXPRESS LLC Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Branaplam | 1562338-42-4 | 98.90% | 393.48 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dihydroergotamine mesylate | 6190-39-2 | 99.9% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amino-PEG8-amine | 82209-36-7 | ≥98.0% | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Nα-Boc-Nω-nitro-D-arginine | 50913-12-7 | MFCD00038091 | 25g Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Selleck Chemical LLC Resiquimod Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Trimethobenzamide hydrochloride | 554-92-7 | 99.9% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pazufloxacin (mesylate) | 163680-77-1 | 100.0% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC ON-01910 25MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More